Topical corticosteroid therapy: clobetasol propionate 0.025%

Topical corticosteroids have been the cornerstone of treatment over last six decades for various dermatoses characterized by dry, scaly, crusted, or erythematous skin as well those associated with inflammation and pruritus. The potency a topical steroid depends on specific molecule, amount drug reaching target, absorption through (0.25%–3%), formulation. Clobetasol propionate (CP) 0.025% cream formulation is potent, fifth-generation corticosteroid. It approved United States Food Drug Administration to be applied twice daily moderate-to–severe psoriasis in adults. This case series covers clinical experience dermatologists, including their expert opinion safety efficacy ImpoyzTM different disorders.